Applications virtualized with Xenocode can be updated with AppLife Update.

To replace the single virtualized exe, the .Net Framework must be present on the host machine and the Xenocode environment must be configured to spawn child processes outside of the VM.

AppLife Update can also update your application by replacing the files within the virtual file system as well.  In this scenario, child processes should not be spawned outside of the VM.  These replaced files will be present, unobfuscated, on the host file system application.