Hello Jorge,

The AppLife Update Service executes your action list update under the security context of the Local System Account.  The local system account uses a system level token under Vista, which has permissions to the registry.

The line in your code sample:

myRegKey = myRegKey.OpenSubKey("\\CLSID\\" + guid + "\\inProcserver32\\");

is returning an null reference.  Remove the leading slashes and this line will behave properly.

myRegKey = myRegKey.OpenSubKey("CLSID\\" + guid + "\\inProcserver32\\");

You might ask why does the original line work except when running under the local system account.  I dont know that answer.  I have succesfully tested this with and without the AppLife Update Service under XP and Vista (32 bit).  The rest I have not tested, but would expect no issues.